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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16961 |
Supinoxin
RX-5902 |
Apoptosis; DNA/RNA Synthesis | Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Supinoxin (RX-5902) 是磷酸化 p68 RNA 解旋酶的强效口服活性抑制剂,是一种抗肿瘤试剂。它与 Y593 磷酸化的 p68 相互作用并减弱 β-catenin 的核穿梭性。它诱导细胞凋亡并抑制 TNBC 癌细胞系的生长,IC50的范围为 10 nM 至 20 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01900 |
DDX5 Protein, Human, Recombinant (His & Myc)
HELR,RNA helicase p68,HLR1,G17P1,... |
Human | E. coli |
DDX5 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 74.1 kDa and the accession number is P17844. |